B-12 Deficiency

Vitamin B12 deficiency is one of the most dangerous vitamin deficiencies. B12 deficiency is a silent epidemic with some serious consequences. B12 deficiency is widespread with approximately 40% of the population being deficient. Worse, your ability to absorb vitamin B12 gradually decreases with age.

B12 Deficiency Symptoms:

  1. Dizziness. Frequent bouts of dizziness, dizzy walking up or down stairs, vertigo or feeling wobbly arising from a sitting position often means low B12.


  1. Forgetfulness. Chronic forgetfulness may indicate a deeper medical issue, but many people suffering from B12 deficiency mistakenly jump to the conclusion they have dementia or Alzheimer’s, when what it really is a B12 deficiency.


  1. Pins and Needles. Pins and needles (or the feeling of numbness) anywhere when you haven’t compressed that part of your body may indicate a B12 deficiency. Numbness or the feeling of electric shock waves can be the result of nerve damage resulting from a B12 deficiency. This all traces back to poor red blood cell production due to a lack of B12.


  1. Fatigue. Have days of yawning and feeling generally fatigued? If that constant fatigue continues for days and weeks, it may be the result of B12 deficiency. The symptoms may be due to a lack of red blood cell production… a vitamin B12 responsibility… meaning oxygen transport to your organs is lacking, causing extreme fatigue.


  1. Vision Issues. B12 deficiency can lead to vision changes and damaged vision causing retinal damage if blood vessels in the eye become blocked. This appears as light sensitivity, blurred or double vision, tracers or shadows, all resulting from optic nerve damage. When you notice persistent health issues like these, you may want to consider a quality B12 supplement.


Supplementing Vitamin B12

There are several methods for supplementing vitamin B12. It is sold as pills, chewables, sprays or by doctors as an injection. Pills and chewables are regarded as the least effective form of absorption. Some companies suggest a mouth spray to get the B12 in the capillaries under the tongue is better.B12

B12 Injections are also effective, but can be expensive and require visits to the doctor.

Methylcobalamin versus Cyanocobalamin

These are the two most widely used forms of B12. Cyanocobalamin is the synthetic form of B12 found in most supplements. Methylcobalamin is the naturally occurring B12 found in nature. When taking a cyanocobalamin supplement the body has to deal with a small, poisonous level of cyanide. During its removal methyl groups of molecules are used. This removal takes from the budget of methyl of this group resulting in a reduction of available methylcobalamin, further stressing the body on a chemical level. It can result in a net negative for your health to take cyanocobalamin. Methylcobalamin is non-toxic, better absorbed and better stored. When searching for a B12 supplement always look for the methylcobalamin and avoid cyanocobalamin. Unfortunately even a trip to the doctor for a B12 injection will likely lead you to cyanocobalamin.

Circadian rhythms –daily brain wave activity, production of hormones, cell generation and other patterns linked to this diurnal cycle— a group of 20 with “normal” B12 levels were given two types of B12, cyanocobalamin or methylcobalamin. Participants given methylcobalamin began sleeping fewer hours than before supplementation. Quality of sleep, concentration and “feeling refreshed” increased from pretreatment through the first week of supplementation, correlating with vitamin B12 plasma levels”. This is just one of many examples of methylcobalamin form of B12 supplementation causing improvements in the behavior of certain functions of the body.

Methylcobalamin specifically benefits the nervous system and addresses any issues that may be caused by B12 deficiency. Cyanocobalamin will not produce the same results. Methylcobalamin is also widely cited as improving sleep and rejuvenation associated with circadian rhythms.  Furthermore, methylcobalamin works with folic acid for some health benefits.

Folic Acid with Vitamin B12

Vitamin B12 and folic acid combine to perform basic genetic and neurologic functions. Not having enough of both can result in some disorders in which complex interactions and masking between levels of minerals they interact with make it difficult to understand the chemical cause of the disorder.



Mayer G., Kroger M., Meier-Ewert K. 1996. Effects of vitamin B12 on performance and circadian rhythm in normal subjects. Neuropsychopharmacology, 1996 Nov. 15: pp. 456-464.

Coppen A, Bolander-Gouaille C. 2005. Treatment of depression: time to consider folic acid and vitamin B12. Annals of the Rheumatic Diseases 1990; Vol. 49, pp. 93-98

Fenech M. 2001. The role of folic acid and Vitamin B12 in genomic stability of human cells. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 18 April 2001, Vol. 475, Issue 1-2, pp. 57-67.